Identification of a transcriptional repressor related to the noncatalytic domain of histone deacetylases 4 and 5

Por Zhou, Xianbo, Richon, Victoria M., Rifkind, Richard A., Marks, Paul A.
Publicado em 2000

Cloning and characterization of a histone deacetylase, HDAC9

Por Zhou, Xianbo, Marks, Paul A., Rifkind, Richard A., Richon, Victoria M.
Publicado em 2001

Histone deacetylase inhibitor selectively induces p21(WAF1) expression and gene-associated histone acetylation

Por Richon, Victoria M., Sandhoff, Todd W., Rifkind, Richard A., Marks, Paul A.
Publicado em 2000

Histone deacetylase 4 associates with extracellular signal-regulated kinases 1 and 2, and its cellular localization is regulated by oncogenic Ras

Por Zhou, Xianbo, Richon, Victoria M., Wang, Audrey H., Yang, Xiang-Jiao, Rifkind, Richard A., Marks, Paul A.
Publicado em 2000

A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases

Por Richon, Victoria M., Emiliani, Stephane, Verdin, Eric, Webb, Yael, Breslow, Ronald, Rifkind, Richard A., Marks, Paul A.
Publicado em 1998

Antileukemia activity of the combination of an anthracycline with a histone deacetylase inhibitor

Por Sanchez-Gonzalez, Blanca, Yang, Hui, Bueso-Ramos, Carlos, Hoshino, Koyu, Quintas-Cardama, Alfonso, Richon, Victoria M., Garcia-Manero, Guillermo
Publicado em 2006

The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin

Por Butler, Lisa M., Zhou, Xianbo, Xu, Wei-Sheng, Scher, Howard I., Rifkind, Richard A., Marks, Paul A., Richon, Victoria M.
Publicado em 2002

Vorinostat in solid and hematologic malignancies

Por Siegel, David, Hussein, Mohamad, Belani, Chandra, Robert, Francisco, Galanis, Evanthia, Richon, Victoria M, Garcia-Vargas, José, Sanz-Rodriguez, Cesar, Rizvi, Syed
Publicado em 2009

Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas

Por Sneeringer, Christopher J., Scott, Margaret Porter, Kuntz, Kevin W., Knutson, Sarah K., Pollock, Roy M., Richon, Victoria M., Copeland, Robert A.
Publicado em 2010

Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia

Por He, Li-Zhen, Tolentino, Thomas, Grayson, Peter, Zhong, Sue, Warrell, Raymond P., Rifkind, Richard A., Marks, Paul A., Richon, Victoria M., Pandolfi, Pier Paolo
Publicado em 2001

Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors

Por Peart, Melissa J., Smyth, Gordon K., van Laar, Ryan K., Bowtell, David D., Richon, Victoria M., Marks, Paul A., Holloway, Andrew J., Johnstone, Ricky W.
Publicado em 2005

Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL)

Por Duvic, Madeleine, Talpur, Rakshandra, Ni, Xiao, Zhang, Chunlei, Hazarika, Parul, Kelly, Cecilia, Chiao, Judy H., Reilly, John F., Ricker, Justin L., Richon, Victoria M., Frankel, Stanley R.
Publicado em 2007

Abrogation of MLL-AF10 and CALM-AF10 mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l

Por Chen, Liying, Deshpande, Aniruddha, Banka, Deepti, Bernt, Kathrin M., Dias, Stuart, Buske, Christian, Olhava, Edward J., Daigle, Scott R., Richon, Victoria M., Pollock, Roy M., Armstrong, Scott A.
Publicado em 2012

Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l

Por Deshpande, Aniruddha J., Chen, Liying, Fazio, Maurizio, Sinha, Amit U., Bernt, Kathrin M., Banka, Deepti, Dias, Stuart, Chang, Jenny, Olhava, Edward J., Daigle, Scott R., Richon, Victoria M., Pollock, Roy M., Armstrong, Scott A.
Publicado em 2013

MLL-rearranged Leukemia is Dependent on Aberrant H3K79 Methylation by DOT1L

Por Bernt, Kathrin M., Zhu, Nan, Sinha, Amit U., Vempati, Sridhar, Faber, Joerg, Krivtsov, Andrei V., Feng, Zhaohui, Punt, Natalie, Daigle, Amanda, Bullinger, Lars, Pollock, Roy M., Richon, Victoria M., Kung, Andrew L., Armstrong, Scott A.
Publicado em 2011

Transcriptional signature of histone deacetylase inhibition in multiple myeloma: Biological and clinical implications

Por Mitsiades, Constantine S., Mitsiades, Nicholas S., McMullan, Ciaran J., Poulaki, Vassiliki, Shringarpure, Reshma, Hideshima, Teru, Akiyama, Masaharu, Chauhan, Dharminder, Munshi, Nikhil, Gu, Xuesong, Bailey, Charles, Joseph, Marie, Libermann, Towia A., Richon, Victoria M., Marks, Paul A., Anderson, Kenneth C.
Publicado em 2004

Durable tumor regression in genetically altered malignant rhabdoid tumors by inhibition of methyltransferase EZH2

Por Knutson, Sarah K., Warholic, Natalie M., Wigle, Tim J., Klaus, Christine R., Allain, Christina J., Raimondi, Alejandra, Porter Scott, Margaret, Chesworth, Richard, Moyer, Mikel P., Copeland, Robert A., Richon, Victoria M., Pollock, Roy M., Kuntz, Kevin W., Keilhack, Heike
Publicado em 2013

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease

Por Hockly, Emma, Richon, Victoria M., Woodman, Benjamin, Smith, Donna L., Zhou, Xianbo, Rosa, Eddie, Sathasivam, Kirupa, Ghazi-Noori, Shabnam, Mahal, Amarbirpal, Lowden, Philip A. S., Steffan, Joan S., Marsh, J. Lawrence, Thompson, Leslie M., Lewis, Cathryn M., Marks, Paul A., Bates, Gillian P.
Publicado em 2003

Phase I Study of an Oral Histone Deacetylase Inhibitor, Suberoylanilide Hydroxamic Acid, in Patients With Advanced Cancer

Por Kelly, William Kevin, O’Connor, Owen A., Lee Krug, M., Chiao, Judy H., Heaney, Mark, Curley, Tracy, MacGregore-Cortelli, Barbara, Tong, William, Secrist, J. Paul, Schwartz, Lawrence, Richardson, Stacy, Chu, Elaina, Olgac, Semra, Marks, Paul A., Scher, Howard, Richon, Victoria M.
Publicado em 2005

Phase II Trial of Vorinostat in Recurrent Glioblastoma Multiforme: A North Central Cancer Treatment Group Study

Por Galanis, Evanthia, Jaeckle, Kurt A., Maurer, Matthew J., Reid, Joel M., Ames, Matthew M., Hardwick, James S., Reilly, John F., Loboda, Andrey, Nebozhyn, Michael, Fantin, Valeria R., Richon, Victoria M., Scheithauer, Bernd, Giannini, Caterina, Flynn, Patrick J., Moore, Dennis F., Zwiebel, James, Buckner, Jan C.
Publicado em 2009