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Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors

Histone deacetylase inhibitors (HDACis) inhibit tumor cell growth and survival, possibly through their ability to regulate the expression of specific proliferative and/or apoptotic genes. However, the HDACi-regulated genes necessary and/or sufficient for their biological effects remain undefined. We...

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Detalhes bibliográficos
Main Authors: Peart, Melissa J., Smyth, Gordon K., van Laar, Ryan K., Bowtell, David D., Richon, Victoria M., Marks, Paul A., Holloway, Andrew J., Johnstone, Ricky W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC552783/
https://ncbi.nlm.nih.gov/pubmed/15738394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500369102
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