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Histone deacetylase inhibitors: potential targets responsible for their anti-cancer effect

The histone deacetylase inhibitors (HDACi) have demonstrated anticancer efficacy across a range of malignancies, most impressively in the hematological cancers. It is uncertain whether this clinical efficacy is attributable predominantly to their ability to induce apoptosis and differentiation in th...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Dickinson, Michael, Johnstone, Ricky W., Prince, H. Miles
פורמט: Artigo
שפה:Inglês
יצא לאור: Springer US 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003794/
https://ncbi.nlm.nih.gov/pubmed/21161327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-010-9596-y
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