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Histone deacetylase inhibitors: potential targets responsible for their anti-cancer effect

The histone deacetylase inhibitors (HDACi) have demonstrated anticancer efficacy across a range of malignancies, most impressively in the hematological cancers. It is uncertain whether this clinical efficacy is attributable predominantly to their ability to induce apoptosis and differentiation in th...

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Bibliografiske detaljer
Main Authors: Dickinson, Michael, Johnstone, Ricky W., Prince, H. Miles
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003794/
https://ncbi.nlm.nih.gov/pubmed/21161327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-010-9596-y
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