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Overview of Histone Deacetylase Inhibitors in Haematological Malignancies
Histone deacetylase inhibitors (HDACi) can induce hyperacetylation of both histone and non-histone target resulting in epigenetic reprogramming and altered activity, stability and localisation of non-histone proteins to ultimately mediate diverse biological effects on cancer cells and their microenv...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4033944/ https://ncbi.nlm.nih.gov/pubmed/27713371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph3082674 |
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