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Overview of Histone Deacetylase Inhibitors in Haematological Malignancies

Histone deacetylase inhibitors (HDACi) can induce hyperacetylation of both histone and non-histone target resulting in epigenetic reprogramming and altered activity, stability and localisation of non-histone proteins to ultimately mediate diverse biological effects on cancer cells and their microenv...

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Detalhes bibliográficos
Main Authors: Bishton, Mark J., Johnstone, Ricky W., Dickinson, Michael, Harrison, Simon, Prince, H. Miles
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033944/
https://ncbi.nlm.nih.gov/pubmed/27713371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph3082674
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