Histone deacetylase inhibitors: clinical implications for hematological malignancies

Histone modifications have widely been implicated in cancer development and progression and are potentially reversible by drug treatments. The N-terminal tails of each histone extend outward through the DNA strand containing amino acid residues modified by posttranslational acetylation, methylation,...

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Bibliographic Details
Main Authors: Tambaro, Francesco Paolo, Dell’Aversana, Carmela, Carafa, Vincenzo, Nebbioso, Angela, Radic, Branka, Ferrara, Felicetto, Altucci, Lucia
Format: Artigo
Language:Inglês
Published: Springer-Verlag 2010
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365365/
https://ncbi.nlm.nih.gov/pubmed/22704087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13148-010-0006-2
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