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Histone deacetylase inhibitors: clinical implications for hematological malignancies
Histone modifications have widely been implicated in cancer development and progression and are potentially reversible by drug treatments. The N-terminal tails of each histone extend outward through the DNA strand containing amino acid residues modified by posttranslational acetylation, methylation,...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer-Verlag
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365365/ https://ncbi.nlm.nih.gov/pubmed/22704087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13148-010-0006-2 |
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