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Dual Tumor Suppressor and Tumor Promoter Action of Sirtuins in Determining Malignant Phenotype

Sirtuins (SIRTs), class III histone deacetylases, are differentially expressed in several human cancers, where they display both oncogenic and tumor-suppressive properties depending on cellular context and experimental conditions. SIRTs are involved in many important biological processes and play a...

詳細記述

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書誌詳細
出版年:Front Pharmacol
主要な著者: Carafa, Vincenzo, Altucci, Lucia, Nebbioso, Angela
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6363704/
https://ncbi.nlm.nih.gov/pubmed/30761005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00038
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