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Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo
BACKGROUND: Calorie restriction (CR) produces a number of health benefits and ameliorates diseases of aging such as type 2 diabetes. The components of the pathways downstream of CR may provide intervention points for developing therapeutics for treating diseases of aging. The NAD(+)-dependent protei...
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Main Authors: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
BioMed Central
2009
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2660283/ https://ncbi.nlm.nih.gov/pubmed/19284563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-3-31 |
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