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Tissue-specific regulation of SIRT1 by calorie restriction

Calorie restriction (CR) has been reported to increase SIRT1 protein levels in mice, rats, and humans, and elevated activity of SIRT1 orthologs extends life span in yeast, worms, and flies. In this study, we challenge the paradigm that CR induces SIRT1 activity in all tissues by showing that activit...

詳細記述

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書誌詳細
主要な著者: Chen, Danica, Bruno, Joanne, Easlon, Erin, Lin, Su-Ju, Cheng, Hwei-Ling, Alt, Frederick W., Guarente, Leonard
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492662/
https://ncbi.nlm.nih.gov/pubmed/18550784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1650608
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