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Calorie restriction extends yeast life span by lowering the level of NADH
Calorie restriction (CR) extends life span in a wide variety of species. Previously, we showed that calorie restriction increases the replicative life span in yeast by activating Sir2, a highly conserved NAD-dependent deacetylase. Here we test whether CR activates Sir2 by increasing the NAD/NADH rat...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC314267/ https://ncbi.nlm.nih.gov/pubmed/14724176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1164804 |
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