Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo

BACKGROUND: Calorie restriction (CR) produces a number of health benefits and ameliorates diseases of aging such as type 2 diabetes. The components of the pathways downstream of CR may provide intervention points for developing therapeutics for treating diseases of aging. The NAD(+)-dependent protei...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Smith, Jesse J, Kenney, Renée Deehan, Gagne, David J, Frushour, Brian P, Ladd, William, Galonek, Heidi L, Israelian, Kristine, Song, Jeffrey, Razvadauskaite, Giedre, Lynch, Amy V, Carney, David P, Johnson, Robin J, Lavu, Siva, Iffland, Andre, Elliott, Peter J, Lambert, Philip D, Elliston, Keith O, Jirousek, Michael R, Milne, Jill C, Boss, Olivier
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2009
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660283/
https://ncbi.nlm.nih.gov/pubmed/19284563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-3-31
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