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ERBB4 is over-expressed in human colon cancer and enhances cellular transformation

The ERBB4 receptor tyrosine kinase promotes colonocyte survival. Herein, we tested whether ERBB4’s antiapoptotic signaling promotes transformation and colorectal tumorigenesis. ERBB4 alterations in a The Cancer Genome Atlas colorectal cancer (CRC) data set stratified survival, and in a combined Moff...

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Publicat a:Carcinogenesis
Autors principals: Williams, Christopher S., Bernard, Jessica K., Demory Beckler, Michelle, Almohazey, Dana, Washington, Mary Kay, Smith, Jesse J., Frey, Mark R.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572918/
https://ncbi.nlm.nih.gov/pubmed/25916654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgv049
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