The ErbB4 Ligand Neuregulin-4 Protects against Experimental Necrotizing Enterocolitis

Necrotizing enterocolitis (NEC) affects up to 10% of premature infants, has a mortality of 30%, and can leave surviving patients with significant morbidity. Neuregulin-4 (NRG4) is an ErbB4-specific ligand that promotes epithelial cell survival. Thus, this pathway could be protective in diseases such...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: McElroy, Steven J., Castle, Shannon L., Bernard, Jessica K., Almohazey, Dana, Hunter, Catherine J., Bell, Brandon A., Al Alam, Denise, Wang, Larry, Ford, Henri R., Frey, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715213/
https://ncbi.nlm.nih.gov/pubmed/25216938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.06.015
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