ERBB4 is over-expressed in human colon cancer and enhances cellular transformation

The ERBB4 receptor tyrosine kinase promotes colonocyte survival. Herein, we tested whether ERBB4’s antiapoptotic signaling promotes transformation and colorectal tumorigenesis. ERBB4 alterations in a The Cancer Genome Atlas colorectal cancer (CRC) data set stratified survival, and in a combined Moff...

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Detalhes bibliográficos
Publicado no:Carcinogenesis
Main Authors: Williams, Christopher S., Bernard, Jessica K., Demory Beckler, Michelle, Almohazey, Dana, Washington, Mary Kay, Smith, Jesse J., Frey, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Original Manuscript
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572918/
https://ncbi.nlm.nih.gov/pubmed/25916654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgv049
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