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MLL-Rearranged Leukemias—An Update on Science and Clinical Approaches

The mixed-lineage leukemia 1 (MLL1) gene (now renamed Lysine [K]-specific MethylTransferase 2A or KMT2A) on chromosome 11q23 is disrupted in a unique group of acute leukemias. More than 80 different partner genes in these fusions have been described, although the majority of leukemias result from ML...

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Detalhes bibliográficos
Publicado no:Front Pediatr
Main Authors: Winters, Amanda C., Bernt, Kathrin M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299633/
https://ncbi.nlm.nih.gov/pubmed/28232907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2017.00004
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