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MLL-Rearranged Leukemias—An Update on Science and Clinical Approaches
The mixed-lineage leukemia 1 (MLL1) gene (now renamed Lysine [K]-specific MethylTransferase 2A or KMT2A) on chromosome 11q23 is disrupted in a unique group of acute leukemias. More than 80 different partner genes in these fusions have been described, although the majority of leukemias result from ML...
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| Veröffentlicht in: | Front Pediatr |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5299633/ https://ncbi.nlm.nih.gov/pubmed/28232907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2017.00004 |
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