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The role of polycomb repressive complex 2 in early T-cell precursor acute lymphoblastic leukemia

Genetic lesions affecting polycomb repressive complex 2 (PRC2) have been found in more than 40% of pediatric cases of early T-cell precursor acute lymphoblastic leukemia. The functional role of these PRC2 alterations has been obscure. Our recent data suggest that compromise of PRC2 blocks differenti...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Bernt, Kathrin M., Neff, Tobias
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154862/
https://ncbi.nlm.nih.gov/pubmed/30263933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1166309
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