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Transient Potential Receptor Melastatin-2 (TRPM2) Does Not Influence Murine MLL-AF9 Driven AML Leukemogenesis or in Vitro Response to Chemotherapy
Transient potential receptor melastatin-2 (TRPM2) is a non-selective cationic, Ca(2+) permeable transmembrane pore that is preferentially expressed in cells of the myeloid lineage, and modulates signaling pathways converging onto NF-kB. This is of potential interest for AML therapy, as NF-κB signali...
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| 發表在: | Exp Hematol |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4914470/ https://ncbi.nlm.nih.gov/pubmed/27033163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2016.03.006 |
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