Transient Receptor Potential Melastatin 2 (TRPM2) ion channel is required for innate immunity against Listeria monocytogenes

The generation of reactive oxygen species (ROS) is inherent to immune responses. ROS are crucially involved in host defense against pathogens by promoting bacterial killing, but also as signaling agents coordinating the production of cytokines. Transient Receptor Potential Melastatin 2 (TRPM2) is a...

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Dettagli Bibliografici
Autori principali: Knowles, Heather, Heizer, Justin W., Li, Yuan, Chapman, Kathryn, Ogden, Carol Anne, Andreasen, Karl, Shapland, Ellen, Kucera, Gary, Mogan, Jennifer, Humann, Jessica, Lenz, Laurel L., Morrison, Alastair D., Perraud, Anne-Laure
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136283/
https://ncbi.nlm.nih.gov/pubmed/21709234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010678108
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