Transient Receptor Potential Melastatin 2 (TRPM2) ion channel is required for innate immunity against Listeria monocytogenes

The generation of reactive oxygen species (ROS) is inherent to immune responses. ROS are crucially involved in host defense against pathogens by promoting bacterial killing, but also as signaling agents coordinating the production of cytokines. Transient Receptor Potential Melastatin 2 (TRPM2) is a...

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Detalhes bibliográficos
Main Authors: Knowles, Heather, Heizer, Justin W., Li, Yuan, Chapman, Kathryn, Ogden, Carol Anne, Andreasen, Karl, Shapland, Ellen, Kucera, Gary, Mogan, Jennifer, Humann, Jessica, Lenz, Laurel L., Morrison, Alastair D., Perraud, Anne-Laure
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136283/
https://ncbi.nlm.nih.gov/pubmed/21709234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010678108
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