Transient Receptor Potential Melastatin 2 (TRPM2) ion channel is required for innate immunity against Listeria monocytogenes

The generation of reactive oxygen species (ROS) is inherent to immune responses. ROS are crucially involved in host defense against pathogens by promoting bacterial killing, but also as signaling agents coordinating the production of cytokines. Transient Receptor Potential Melastatin 2 (TRPM2) is a...

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Bibliographische Detailangaben
Hauptverfasser: Knowles, Heather, Heizer, Justin W., Li, Yuan, Chapman, Kathryn, Ogden, Carol Anne, Andreasen, Karl, Shapland, Ellen, Kucera, Gary, Mogan, Jennifer, Humann, Jessica, Lenz, Laurel L., Morrison, Alastair D., Perraud, Anne-Laure
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136283/
https://ncbi.nlm.nih.gov/pubmed/21709234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010678108
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