The Pharmacological Landscape and Therapeutic Potential of Serine Hydrolases

od Bachovchin, Daniel A., Cravatt, Benjamin F.
Izdano 2012

Pyroptosis and apoptosis pathways engage in bidirectional crosstalk in monocytes and macrophages

od Taabazuing, Cornelius Y., Okondo, Marian C., Bachovchin, Daniel A.
izdano v Cell Chem Biol (2017)

The NLRP1 and CARD8 inflammasomes

od Taabazuing, Cornelius Y., Griswold, Andrew R., Bachovchin, Daniel A.
izdano v Immunol Rev (2020)

Substrate-Free High-Throughput Screening Identifies Selective Inhibitors for Uncharacterized Enzymes

od Bachovchin, Daniel A., Brown, Steven J., Rosen, Hugh, Cravatt, Benjamin F.
Izdano 2009

α-Lytic protease can exist in two separately stable conformations with different His(57) mobilities and catalytic activities

od Haddad, Kristin Coffman, Sudmeier, James L., Bachovchin, Daniel A., Bachovchin, William W.
Izdano 2005

Rapid Development of a Potent Photo-Triggered Inhibitor of the Serine Hydrolase RBBP9

od Liu, Xiaodan, Dix, Melissa, Speers, Anna E., Bachovchin, Daniel A., Zuhl, Andrea M., Cravatt, Benjamin F., Kodadek, Thomas
Izdano 2012

Click-generated triazole ureas as ultrapotent, in vivo-active serine hydrolase inhibitors

od Adibekian, Alexander, Martin, Brent R., Wang, Chu, Hsu, Ku-Lung, Bachovchin, Daniel A., Niessen, Sherry, Hoover, Heather, Cravatt, Benjamin F.
Izdano 2011

DPP8/9 inhibitors are universal activators of functional NLRP1 alleles

od Gai, Kuo, Okondo, Marian C., Rao, Sahana D., Chui, Ashley J., Ball, Daniel P., Johnson, Darren C., Bachovchin, Daniel A.
izdano v Cell Death Dis (2019)

DPP9’s Enzymatic Activity and Not Its Binding to CARD8 Inhibits Inflammasome Activation

od Griswold, Andrew R., Ball, Daniel P., Bhattacharjee, Abir, Chui, Ashley J., Rao, Sahana D., Taabazuing, Cornelius Y., Bachovchin, Daniel A.
izdano v ACS Chem Biol (2019)

Potent and Selective Inhibitors of Glutathione S-transferase Omega 1 that Impair Cancer Drug Resistance

od Tsuboi, Katsunori, Bachovchin, Daniel A., Speers, Anna E., Spicer, Timothy P., Fernandez-Vega, Virneliz, Hodder, Peter, Rosen, Hugh, Cravatt, Benjamin F.
Izdano 2011

Novel Inhibitors for PRMT1 Discovered by High–Throughput Screening Using Activity–Based Fluorescence Polarization

od Dillon, Myles B. C., Bachovchin, Daniel A., Brown, Steven J., Finn, M.G., Rosen, Hugh, Cravatt, Benjamin F., Mowen, Kerri A.
Izdano 2012

Inhibition of Dpp8/9 Activates the Nlrp1b Inflammasome

od Okondo, Marian C., Rao, Sahana D., Taabazuing, Cornelius Y., Chui, Ashley J., Poplawski, Sarah E., Johnson, Darren C., Bachovchin, Daniel A.
izdano v Cell Chem Biol (2018)

DPP8/9 inhibitors activate the CARD8 inflammasome in resting lymphocytes

od Johnson, Darren C., Okondo, Marian C., Orth, Elizabeth L., Rao, Sahana D., Huang, Hsin-Che, Ball, Daniel P., Bachovchin, Daniel A.
izdano v Cell Death Dis (2020)

Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening

od Bachovchin, Daniel A., Ji, Tianyang, Li, Weiwei, Simon, Gabriel M., Blankman, Jacqueline L., Adibekian, Alexander, Hoover, Heather, Niessen, Sherry, Cravatt, Benjamin F.
Izdano 2010

Discovery and Optimization of Sulfonyl Acrylonitriles as Selective, Covalent Inhibitors of Protein Phosphatase Methylesterase-1

od Bachovchin, Daniel A., Zuhl, Andrea M., Speers, Anna E., Wolfe, Monique R., Weerapana, Eranthie, Brown, Steven J., Rosen, Hugh, Cravatt, Benjamin F.
Izdano 2011

A chemical strategy for protease substrate profiling

od Griswold, Andrew R., Cifani, Paolo, Rao, Sahana D., Axelrod, Abram J., Miele, Matthew M., Hendrickson, Ronald C., Kentsis, Alex, Bachovchin, Daniel A.
izdano v Cell Chem Biol (2019)

A Fluopol-ABPP HTS Assay to Identify PAD Inhibitors

od Knuckley, Bryan, Jones, Justin E., Bachovchin, Daniel A., Slack, Jessica, Causey, Corey P., Brown, Steven J., Rosen, Hugh, Cravatt, Benjamin F., Thompson, Paul R.
Izdano 2010

Quantitative reactivity profiling predicts functional cysteines in proteomes

od Weerapana, Eranthie, Wang, Chu, Simon, Gabriel M., Richter, Florian, Khare, Sagar, Dillon, Myles B.D., Bachovchin, Daniel A., Mowen, Kerri, Baker, David, Cravatt, Benjamin F.
Izdano 2010

Oxime esters as selective, covalent inhibitors of the serine hydrolase retinoblastoma-binding protein 9 (RBBP9)

od Bachovchin, Daniel A., Wolfe, Monique R., Masuda, Kim, Brown, Steven J., Spicer, Timothy P., Fernandez-Vega, Virneliz, Chase, Peter, Hodder, Peter S., Rosen, Hugh, Cravatt, Benjamin F.
Izdano 2010

Activation of the CARD8 Inflammasome Requires a Disordered Region

od Chui, Ashley J., Griswold, Andrew R., Taabazuing, Cornelius Y., Orth, Elizabeth L., Gai, Kuo, Rao, Sahana D., Ball, Daniel P., Hsiao, Jeffrey C., Bachovchin, Daniel A.
izdano v Cell Rep (2020)