α-Lytic protease can exist in two separately stable conformations with different His(57) mobilities and catalytic activities

по Haddad, Kristin Coffman, Sudmeier, James L., Bachovchin, Daniel A., Bachovchin, William W.
Опубликовано 2005

GLP-1(32-36)amide Pentapeptide Increases Basal Energy Expenditure and Inhibits Weight Gain in Obese Mice

по Tomas, Eva, Stanojevic, Violeta, McManus, Karen, Khatri, Ashok, Everill, Paul, Bachovchin, William W., Habener, Joel F.
Опубликовано в: Diabetes (2015)

Human FGF-21 Is a Substrate of Fibroblast Activation Protein

по Coppage, Andrew L., Heard, Kathryn R., DiMare, Matthew T., Liu, Yuxin, Wu, Wengen, Lai, Jack H., Bachovchin, William W.
Опубликовано в: PLoS One (2016)

Circulating Fibroblast Activation Protein and Dipeptidyl Peptidase 4 in Rheumatoid Arthritis and Systemic Sclerosis

по Sinnathurai, Premarani, Lau, Wendy, de Ribeiro, Ana Julia Vieira, Bachovchin, William W, Englert, Helen, Howe, Graydon, Spencer, David, Manolios, Nicholas, Gorrell, Mark D.
Опубликовано в: Int J Rheum Dis (2016)

Tautomerism, acid-base equilibria, and H-bonding of the six histidines in subtilisin BPN′ by NMR

по Day, Regina M., Thalhauser, Craig J., Sudmeier, James L., Vincent, Matthew P., Torchilin, Ekaterina V., Sanford, David G., Bachovchin, Christopher W., Bachovchin, William W.
Опубликовано 2003

Unusual (1)H NMR chemical shifts support (His) C(ɛ)(1)—H⋅⋅⋅O⩵C H-bond: Proposal for reaction-driven ring flip mechanism in serine protease catalysis

по Ash, Elissa L., Sudmeier, James L., Day, Regina M., Vincent, Matthew, Torchilin, Ekaterina V., Haddad, Kristin Coffman, Bradshaw, Elizabeth M., Sanford, David G., Bachovchin, William W.
Опубликовано 2000

Identification of Selective and Potent Inhibitors of Fibroblast Activation Protein and Prolyl Oligopeptidase

по Poplawski, Sarah E., Lai, Jack H., Li, Youhua, Jin, Zhiping, Liu, Yuxin, Wu, Wengen, Wu, Yong, Zhou, Yuhong, Sudmeier, James L., Sanford, David G., Bachovchin, William W.
Опубликовано 2013

Fibroblast activation protein is dispensable for control of glucose homeostasis and body weight in mice

по Panaro, Brandon L., Coppage, Andrew L., Beaudry, Jacqueline L., Varin, Elodie M., Kaur, Kirandeep, Lai, Jack H., Wu, Wengen, Liu, Yuxin, Bachovchin, William W., Drucker, Daniel J.
Опубликовано в: Mol Metab (2018)

A pan inhibitor of DASH family enzymes induces immunogenic modulation and sensitizes murine and human carcinoma cells to antigen-specific cytotoxic T lymphocyte killing: implicatio...

по Donahue, Renee N., Duncan, Brynn B., Fry, Terry J., Jones, Barry, Bachovchin, William W., Kiritsy, Christopher P., Lai, Jack H., Wu, Wengen, Zhao, Peng, Liu, Yuxin, Tsang, Kwong-Yok, Hodge, James W.
Опубликовано 2014

A pan-inhibitor of DASH family enzymes induces immune-mediated regression of murine sarcoma and is a potent adjuvant to dendritic cell vaccination and adoptive T-cell therapy

по Duncan, Brynn B., Highfill, Steven L., Qin, Haiying, Bouchkouj, Najat, Larabee, Shannon, Zhao, Peng, Woznica, Iwona, Liu, Yuxin, Li, Youhua, Wu, Wengen, Lai, Jack H., Jones, Barry, Mackall, Crystal L., Bachovchin, William W., Fry, Terry J.
Опубликовано 2013

Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice

по Fan, Ming-Hui, Zhu, Qiang, Li, Hui-Hua, Ra, Hyun-Jeong, Majumdar, Sonali, Gulick, Dexter L., Jerome, Jacob A., Madsen, Daniel H., Christofidou-Solomidou, Melpo, Speicher, David W., Bachovchin, William W., Feghali-Bostwick, Carol, Puré, Ellen
Опубликовано в: J Biol Chem (2016)

DPP8/9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis

по Okondo, Marian C., Johnson, Darren C., Sridharan, Ramya, Go, Eun Bin, Chui, Ashley J., Wang, Mitchell S., Poplawski, Sarah E., Wu, Wengen, Liu, Yuxin, Lai, Jack H., Sanford, David G., Arciprete, Michael O., Golub, Todd R., Bachovchin, William W., Bachovchin, Daniel A.
Опубликовано в: Nat Chem Biol (2016)

A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity

по Bachovchin, Daniel A., Koblan, Luke W., Wu, Wengen, Liu, Yuxin, Li, Youhua, Zhao, Peng, Woznica, Iwona, Shu, Ying, Lai, Jack H., Poplawski, Sarah E., Kiritsy, Christopher P., Healey, Sarah E., DiMare, Matthew, Sanford, David G., Munford, Robert S., Bachovchin, William W., Golub, Todd R.
Опубликовано в: Nat Chem Biol (2014)

Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs()

по Keane, Fiona M., Yao, Tsun-Wen, Seelk, Stefanie, Gall, Margaret G., Chowdhury, Sumaiya, Poplawski, Sarah E., Lai, Jack H., Li, Youhua, Wu, Wengen, Farrell, Penny, Vieira de Ribeiro, Ana Julia, Osborne, Brenna, Yu, Denise M.T., Seth, Devanshi, Rahman, Khairunnessa, Haber, Paul, Topaloglu, A. Kemal, Wang, Chuanmin, Thomson, Sally, Hennessy, Annemarie, Prins, John, Twigg, Stephen M., McLennan, Susan V., McCaughan, Geoffrey W., Bachovchin, William W., Gorrell, Mark D.
Опубликовано 2013

An atypical parvovirus driving chronic tubulointerstitial nephropathy and kidney fibrosis

по Roediger, Ben, Lee, Quintin, Tikoo, Shweta, Cobbin, Joanna C. A., Henderson, James M., Jormakka, Mika, O’Rourke, Matthew B., Padula, Matthew P., Pinello, Natalia, Henry, Marisa, Wynne, Maria, Santagostino, Sara F., Brayton, Cory F., Rasmussen, Lorna, Lisowski, Leszek, Tay, Szun S., Harris, David C., Bertram, John F., Dowling, John P., Bertolino, Patrick, Lai, Jack H., Wu, Wengen, Bachovchin, William W., Wong, Justin J.-L., Gorrell, Mark D., Shaban, Babak, Holmes, Edward C., Jolly, Christopher J., Monette, Sébastien, Weninger, Wolfgang
Опубликовано в: Cell (2018)