Identification of Selective and Potent Inhibitors of Fibroblast Activation Protein and Prolyl Oligopeptidase

[Image: see text] Fibroblast activation protein (FAP) is a serine protease selectively expressed on reactive stromal fibroblasts of epithelial carcinomas. It is widely believed to play a role in tumor invasion and metastasis and therefore to represent a potential new drug target for cancer. Investig...

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Hlavní autoři: Poplawski, Sarah E., Lai, Jack H., Li, Youhua, Jin, Zhiping, Liu, Yuxin, Wu, Wengen, Wu, Yong, Zhou, Yuhong, Sudmeier, James L., Sanford, David G., Bachovchin, William W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059180/
https://ncbi.nlm.nih.gov/pubmed/23594271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm400351a
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