Inhibition of Dpp8/9 Activates the Nlrp1b Inflammasome

Por Okondo, Marian C., Rao, Sahana D., Taabazuing, Cornelius Y., Chui, Ashley J., Poplawski, Sarah E., Johnson, Darren C., Bachovchin, Daniel A.
Publicado no Cell Chem Biol (2018)

Identification of Selective and Potent Inhibitors of Fibroblast Activation Protein and Prolyl Oligopeptidase

Por Poplawski, Sarah E., Lai, Jack H., Li, Youhua, Jin, Zhiping, Liu, Yuxin, Wu, Wengen, Wu, Yong, Zhou, Yuhong, Sudmeier, James L., Sanford, David G., Bachovchin, William W.
Publicado em 2013

DPP8/9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis

Por Okondo, Marian C., Johnson, Darren C., Sridharan, Ramya, Go, Eun Bin, Chui, Ashley J., Wang, Mitchell S., Poplawski, Sarah E., Wu, Wengen, Liu, Yuxin, Lai, Jack H., Sanford, David G., Arciprete, Michael O., Golub, Todd R., Bachovchin, William W., Bachovchin, Daniel A.
Publicado no Nat Chem Biol (2016)

A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity

Por Bachovchin, Daniel A., Koblan, Luke W., Wu, Wengen, Liu, Yuxin, Li, Youhua, Zhao, Peng, Woznica, Iwona, Shu, Ying, Lai, Jack H., Poplawski, Sarah E., Kiritsy, Christopher P., Healey, Sarah E., DiMare, Matthew, Sanford, David G., Munford, Robert S., Bachovchin, William W., Golub, Todd R.
Publicado no Nat Chem Biol (2014)

Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs()

Por Keane, Fiona M., Yao, Tsun-Wen, Seelk, Stefanie, Gall, Margaret G., Chowdhury, Sumaiya, Poplawski, Sarah E., Lai, Jack H., Li, Youhua, Wu, Wengen, Farrell, Penny, Vieira de Ribeiro, Ana Julia, Osborne, Brenna, Yu, Denise M.T., Seth, Devanshi, Rahman, Khairunnessa, Haber, Paul, Topaloglu, A. Kemal, Wang, Chuanmin, Thomson, Sally, Hennessy, Annemarie, Prins, John, Twigg, Stephen M., McLennan, Susan V., McCaughan, Geoffrey W., Bachovchin, William W., Gorrell, Mark D.
Publicado em 2013