Suppression of Tumor Growth in Mice by Rationally Designed Pseudopeptide Inhibitors of Fibroblast Activation Protein and Prolyl Oligopeptidase()

Tumor microenvironments (TMEs) are composed of cancer cells, fibroblasts, extracellular matrix, microvessels, and endothelial cells. Two prolyl endopeptidases, fibroblast activation protein (FAP) and prolyl oligopeptidase (POP), are commonly overexpressed by epithelial-derived malignancies, with the...

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Publicado no:Neoplasia
Main Authors: Jackson, Kenneth W., Christiansen, Victoria J., Yadav, Vivek R., Silasi-Mansat, Robert, Lupu, Florea, Awasthi, Vibhudutta, Zhang, Roy R., McKee, Patrick A.
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309729/
https://ncbi.nlm.nih.gov/pubmed/25622898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2014.11.002
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