An atypical parvovirus driving chronic tubulointerstitial nephropathy and kidney fibrosis

The occurrence of a spontaneous nephropathy with intranuclear inclusions in laboratory mice has puzzled pathologists for over four decades. While the condition is more severe in immunodeficient animals suggesting an infectious cause, its etiology has remained elusive. Using metagenomics, we identify...

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Publicado en:Cell
Main Authors: Roediger, Ben, Lee, Quintin, Tikoo, Shweta, Cobbin, Joanna C. A., Henderson, James M., Jormakka, Mika, O’Rourke, Matthew B., Padula, Matthew P., Pinello, Natalia, Henry, Marisa, Wynne, Maria, Santagostino, Sara F., Brayton, Cory F., Rasmussen, Lorna, Lisowski, Leszek, Tay, Szun S., Harris, David C., Bertram, John F., Dowling, John P., Bertolino, Patrick, Lai, Jack H., Wu, Wengen, Bachovchin, William W., Wong, Justin J.-L., Gorrell, Mark D., Shaban, Babak, Holmes, Edward C., Jolly, Christopher J., Monette, Sébastien, Weninger, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800251/
https://ncbi.nlm.nih.gov/pubmed/30220458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.08.013
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