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Human FGF-21 Is a Substrate of Fibroblast Activation Protein
FGF-21 is a key regulator of metabolism and potential drug candidate for the treatment of type II diabetes and other metabolic disorders. However, the half-life of active, circulating, human FGF-21 has recently been shown to be limited in mice and monkeys by a proteolytic cleavage between P171 and S...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4786124/ https://ncbi.nlm.nih.gov/pubmed/26962859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151269 |
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