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Mechanisms of Action of Methionine Restriction and Fibroblast Growth Factor 21 (FGF21)
OBJECTIVES: Many of the metabolic benefits of methionine restriction (MR) are mediated by FGF21. MR activates protein kinase R-like ER kinase (PERK) and nuclear respiratory factor 2 (NRF2) signaling pathways, which have also been tied to FGF21 production. Aim 1 is to elucidate the mechanism by which...
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| Publicado no: | Curr Dev Nutr |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7257459/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzaa057_034 |
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