Mechanisms of Action of Methionine Restriction and Fibroblast Growth Factor 21 (FGF21)

OBJECTIVES: Many of the metabolic benefits of methionine restriction (MR) are mediated by FGF21. MR activates protein kinase R-like ER kinase (PERK) and nuclear respiratory factor 2 (NRF2) signaling pathways, which have also been tied to FGF21 production. Aim 1 is to elucidate the mechanism by which...

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Vydáno v:Curr Dev Nutr
Hlavní autoři: Land, Hannah, West, Chloe, Stern, Javier, Gettys, Thomas, Wanders, Desiree, Perez, Patricia, Chiang, Kathryn
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Neuroscience, Nutrition and the Brain
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7257459/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzaa057_034
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