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FGF21 Mediates the Thermogenic and Insulin-Sensitizing Effects of Dietary Methionine Restriction but Not Its Effects on Hepatic Lipid Metabolism

Dietary methionine restriction (MR) produces a rapid and persistent remodeling of white adipose tissue (WAT), an increase in energy expenditure (EE), and enhancement of insulin sensitivity. Recent work established that hepatic expression of FGF21 is robustly increased by MR. Fgf21(−/−) mice were use...

詳細記述

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書誌詳細
出版年:Diabetes
主要な著者: Wanders, Desiree, Forney, Laura A., Stone, Kirsten P., Burk, David H., Pierse, Alicia, Gettys, Thomas W.
フォーマット: Artigo
言語:Inglês
出版事項: American Diabetes Association 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360300/
https://ncbi.nlm.nih.gov/pubmed/28096260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-1212
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