Fibroblast activation protein is dispensable for control of glucose homeostasis and body weight in mice

OBJECTIVE: Fibroblast Activation Protein (FAP), an enzyme structurally related to dipeptidyl peptidase-4 (DPP-4), has garnered interest as a potential metabolic drug target due to its ability to cleave and inactivate FGF-21 as well as other peptide substrates. Here we investigated the metabolic impo...

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Vydáno v:Mol Metab
Hlavní autoři: Panaro, Brandon L., Coppage, Andrew L., Beaudry, Jacqueline L., Varin, Elodie M., Kaur, Kirandeep, Lai, Jack H., Wu, Wengen, Liu, Yuxin, Bachovchin, William W., Drucker, Daniel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323180/
https://ncbi.nlm.nih.gov/pubmed/30477988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.10.011
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