Fibroblast activation protein is dispensable for control of glucose homeostasis and body weight in mice

OBJECTIVE: Fibroblast Activation Protein (FAP), an enzyme structurally related to dipeptidyl peptidase-4 (DPP-4), has garnered interest as a potential metabolic drug target due to its ability to cleave and inactivate FGF-21 as well as other peptide substrates. Here we investigated the metabolic impo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Metab
Prif Awduron: Panaro, Brandon L., Coppage, Andrew L., Beaudry, Jacqueline L., Varin, Elodie M., Kaur, Kirandeep, Lai, Jack H., Wu, Wengen, Liu, Yuxin, Bachovchin, William W., Drucker, Daniel J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2018
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323180/
https://ncbi.nlm.nih.gov/pubmed/30477988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.10.011
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