The brown adipose tissue glucagon receptor is functional but not essential for control of energy homeostasis in mice

OBJECTIVE: Administration of glucagon (GCG) or GCG-containing co-agonists reduces body weight and increases energy expenditure. These actions appear to be transduced by multiple direct and indirect GCG receptor (GCGR)-dependent mechanisms. Although the canonical GCGR is expressed in brown adipose ti...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Metab
Hauptverfasser: Beaudry, Jacqueline L., Kaur, Kiran Deep, Varin, Elodie M., Baggio, Laurie L., Cao, Xiemin, Mulvihill, Erin E., Stern, Jennifer H., Campbell, Jonathan E., Scherer, Phillip E., Drucker, Daniel J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
Schlagworte:
Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437632/
https://ncbi.nlm.nih.gov/pubmed/30772257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.01.011
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