Hematopoietic cell– versus enterocyte-derived dipeptidyl peptidase-4 differentially regulates triglyceride excursion in mice

Postprandial triglycerides (TGs) are elevated in people with type 2 diabetes (T2D). Glucose-lowering agents, such as glucagon-like peptide-1 (GLP-1) receptor agonists and dipeptidyl peptidase-4 (DPP-4) inhibitors, also reduce postprandial TG excursion. Although the glucose-lowering mechanisms of DPP...

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Pubblicato in:JCI Insight
Autori principali: Varin, Elodie M., Hanson, Antonio A., Beaudry, Jacqueline L., Nguyen, My-Anh, Cao, Xiemin, Baggio, Laurie L., Mulvihill, Erin E., Drucker, Daniel J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455127/
https://ncbi.nlm.nih.gov/pubmed/32663193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140418
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