TCF7 is not essential for glucose homeostasis in mice

OBJECTIVE: Glucose-dependent insulinotropic polypeptide (GIP) and Glucagon-like peptide-1 (GLP-1) are incretin hormones that exert overlapping yet distinct actions on islet β-cells. We recently observed that GIP, but not GLP-1, upregulated islet expression of Transcription Factor 7 (TCF7), a gene ex...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Metab
Prif Awduron: Kaur, Kiran Deep, Wong, Chi Kin, Baggio, Laurie L., Beaudry, Jacqueline L., Fuchs, Shai, Panaro, Brandon L., Matthews, Dianne, Cao, Xiemin, Drucker, Daniel J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2021
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8086146/
https://ncbi.nlm.nih.gov/pubmed/33741532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2021.101213
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