TCF7 is not essential for glucose homeostasis in mice

OBJECTIVE: Glucose-dependent insulinotropic polypeptide (GIP) and Glucagon-like peptide-1 (GLP-1) are incretin hormones that exert overlapping yet distinct actions on islet β-cells. We recently observed that GIP, but not GLP-1, upregulated islet expression of Transcription Factor 7 (TCF7), a gene ex...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Kaur, Kiran Deep, Wong, Chi Kin, Baggio, Laurie L., Beaudry, Jacqueline L., Fuchs, Shai, Panaro, Brandon L., Matthews, Dianne, Cao, Xiemin, Drucker, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8086146/
https://ncbi.nlm.nih.gov/pubmed/33741532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2021.101213
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