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Gut-Proglucagon-Derived Peptides Are Essential for Regulating Glucose Homeostasis in Mice

The importance of pancreatic versus intestinal-derived GLP-1 for glucose homeostasis is controversial. We detected active GLP-1 in the mouse and human pancreas, albeit at extremely low levels relative to glucagon. Accordingly, to elucidate the metabolic importance of intestinal proglucagon-derived p...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Metab
Egile Nagusiak: Song, Youngmi, Koehler, Jacqueline A., Baggio, Laurie L., Powers, Alvin C., Sandoval, Darleen A., Drucker, Daniel J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8140521/
https://ncbi.nlm.nih.gov/pubmed/31495689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.08.009
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