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The brown adipose tissue glucagon receptor is functional but not essential for control of energy homeostasis in mice

OBJECTIVE: Administration of glucagon (GCG) or GCG-containing co-agonists reduces body weight and increases energy expenditure. These actions appear to be transduced by multiple direct and indirect GCG receptor (GCGR)-dependent mechanisms. Although the canonical GCGR is expressed in brown adipose ti...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Metab
मुख्य लेखकों: Beaudry, Jacqueline L., Kaur, Kiran Deep, Varin, Elodie M., Baggio, Laurie L., Cao, Xiemin, Mulvihill, Erin E., Stern, Jennifer H., Campbell, Jonathan E., Scherer, Phillip E., Drucker, Daniel J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Elsevier 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437632/
https://ncbi.nlm.nih.gov/pubmed/30772257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.01.011
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