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The NLRP1 and CARD8 inflammasomes

Inflammasomes are multiprotein complexes that activate inflammatory cytokines and induce pyroptosis in response to intracellular danger‐associated signals. NLRP1 and CARD8 are related germline‐encoded pattern recognition receptors that form inflammasomes, but their activation mechanisms and biologic...

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Bibliografiske detaljer
Udgivet i:Immunol Rev
Main Authors: Taabazuing, Cornelius Y., Griswold, Andrew R., Bachovchin, Daniel A.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483925/
https://ncbi.nlm.nih.gov/pubmed/32558991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12884
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