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DPP9’s Enzymatic Activity and Not Its Binding to CARD8 Inhibits Inflammasome Activation
[Image: see text] Inflammasomes are multiprotein complexes formed in response to pathogens. NLRP1 and CARD8 are related proteins that form inflammasomes, but the pathogen-associated signal(s) and the molecular mechanisms controlling their activation have not been established. Inhibitors of the serin...
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| Publicado no: | ACS Chem Biol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2019
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6862324/ https://ncbi.nlm.nih.gov/pubmed/31525884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00462 |
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