The Pharmacological Landscape and Therapeutic Potential of Serine Hydrolases

द्वारा Bachovchin, Daniel A., Cravatt, Benjamin F.
प्रकाशित 2012

Pyroptosis and apoptosis pathways engage in bidirectional crosstalk in monocytes and macrophages

द्वारा Taabazuing, Cornelius Y., Okondo, Marian C., Bachovchin, Daniel A.
में प्रकाशित Cell Chem Biol (2017)

The NLRP1 and CARD8 inflammasomes

द्वारा Taabazuing, Cornelius Y., Griswold, Andrew R., Bachovchin, Daniel A.
में प्रकाशित Immunol Rev (2020)

Substrate-Free High-Throughput Screening Identifies Selective Inhibitors for Uncharacterized Enzymes

द्वारा Bachovchin, Daniel A., Brown, Steven J., Rosen, Hugh, Cravatt, Benjamin F.
प्रकाशित 2009

α-Lytic protease can exist in two separately stable conformations with different His(57) mobilities and catalytic activities

द्वारा Haddad, Kristin Coffman, Sudmeier, James L., Bachovchin, Daniel A., Bachovchin, William W.
प्रकाशित 2005

Rapid Development of a Potent Photo-Triggered Inhibitor of the Serine Hydrolase RBBP9

द्वारा Liu, Xiaodan, Dix, Melissa, Speers, Anna E., Bachovchin, Daniel A., Zuhl, Andrea M., Cravatt, Benjamin F., Kodadek, Thomas
प्रकाशित 2012

Click-generated triazole ureas as ultrapotent, in vivo-active serine hydrolase inhibitors

द्वारा Adibekian, Alexander, Martin, Brent R., Wang, Chu, Hsu, Ku-Lung, Bachovchin, Daniel A., Niessen, Sherry, Hoover, Heather, Cravatt, Benjamin F.
प्रकाशित 2011

DPP8/9 inhibitors are universal activators of functional NLRP1 alleles

द्वारा Gai, Kuo, Okondo, Marian C., Rao, Sahana D., Chui, Ashley J., Ball, Daniel P., Johnson, Darren C., Bachovchin, Daniel A.
में प्रकाशित Cell Death Dis (2019)

DPP9’s Enzymatic Activity and Not Its Binding to CARD8 Inhibits Inflammasome Activation

द्वारा Griswold, Andrew R., Ball, Daniel P., Bhattacharjee, Abir, Chui, Ashley J., Rao, Sahana D., Taabazuing, Cornelius Y., Bachovchin, Daniel A.
में प्रकाशित ACS Chem Biol (2019)

Potent and Selective Inhibitors of Glutathione S-transferase Omega 1 that Impair Cancer Drug Resistance

द्वारा Tsuboi, Katsunori, Bachovchin, Daniel A., Speers, Anna E., Spicer, Timothy P., Fernandez-Vega, Virneliz, Hodder, Peter, Rosen, Hugh, Cravatt, Benjamin F.
प्रकाशित 2011

Novel Inhibitors for PRMT1 Discovered by High–Throughput Screening Using Activity–Based Fluorescence Polarization

द्वारा Dillon, Myles B. C., Bachovchin, Daniel A., Brown, Steven J., Finn, M.G., Rosen, Hugh, Cravatt, Benjamin F., Mowen, Kerri A.
प्रकाशित 2012

Inhibition of Dpp8/9 Activates the Nlrp1b Inflammasome

द्वारा Okondo, Marian C., Rao, Sahana D., Taabazuing, Cornelius Y., Chui, Ashley J., Poplawski, Sarah E., Johnson, Darren C., Bachovchin, Daniel A.
में प्रकाशित Cell Chem Biol (2018)

DPP8/9 inhibitors activate the CARD8 inflammasome in resting lymphocytes

द्वारा Johnson, Darren C., Okondo, Marian C., Orth, Elizabeth L., Rao, Sahana D., Huang, Hsin-Che, Ball, Daniel P., Bachovchin, Daniel A.
में प्रकाशित Cell Death Dis (2020)

Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening

द्वारा Bachovchin, Daniel A., Ji, Tianyang, Li, Weiwei, Simon, Gabriel M., Blankman, Jacqueline L., Adibekian, Alexander, Hoover, Heather, Niessen, Sherry, Cravatt, Benjamin F.
प्रकाशित 2010

Discovery and Optimization of Sulfonyl Acrylonitriles as Selective, Covalent Inhibitors of Protein Phosphatase Methylesterase-1

द्वारा Bachovchin, Daniel A., Zuhl, Andrea M., Speers, Anna E., Wolfe, Monique R., Weerapana, Eranthie, Brown, Steven J., Rosen, Hugh, Cravatt, Benjamin F.
प्रकाशित 2011

A chemical strategy for protease substrate profiling

द्वारा Griswold, Andrew R., Cifani, Paolo, Rao, Sahana D., Axelrod, Abram J., Miele, Matthew M., Hendrickson, Ronald C., Kentsis, Alex, Bachovchin, Daniel A.
में प्रकाशित Cell Chem Biol (2019)

A Fluopol-ABPP HTS Assay to Identify PAD Inhibitors

द्वारा Knuckley, Bryan, Jones, Justin E., Bachovchin, Daniel A., Slack, Jessica, Causey, Corey P., Brown, Steven J., Rosen, Hugh, Cravatt, Benjamin F., Thompson, Paul R.
प्रकाशित 2010

Quantitative reactivity profiling predicts functional cysteines in proteomes

द्वारा Weerapana, Eranthie, Wang, Chu, Simon, Gabriel M., Richter, Florian, Khare, Sagar, Dillon, Myles B.D., Bachovchin, Daniel A., Mowen, Kerri, Baker, David, Cravatt, Benjamin F.
प्रकाशित 2010

Oxime esters as selective, covalent inhibitors of the serine hydrolase retinoblastoma-binding protein 9 (RBBP9)

द्वारा Bachovchin, Daniel A., Wolfe, Monique R., Masuda, Kim, Brown, Steven J., Spicer, Timothy P., Fernandez-Vega, Virneliz, Chase, Peter, Hodder, Peter S., Rosen, Hugh, Cravatt, Benjamin F.
प्रकाशित 2010

Activation of the CARD8 Inflammasome Requires a Disordered Region

द्वारा Chui, Ashley J., Griswold, Andrew R., Taabazuing, Cornelius Y., Orth, Elizabeth L., Gai, Kuo, Rao, Sahana D., Ball, Daniel P., Hsiao, Jeffrey C., Bachovchin, Daniel A.
में प्रकाशित Cell Rep (2020)