Structural Basis of Mycobacterial Inhibition by Cyclomarin A

Por Vasudevan, Dileep, Rao, Srinivasa P. S., Noble, Christian G.
Publicado em 2013

The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis

Por Rao, Srinivasa P. S., Alonso, Sylvie, Rand, Lucinda, Dick, Thomas, Pethe, Kevin
Publicado em 2008

Characterization of Phosphofructokinase Activity in Mycobacterium tuberculosis Reveals That a Functional Glycolytic Carbon Flow Is Necessary to Limit the Accumulation of Toxic Meta...

Por Phong, Wai Yee, Lin, Wenwei, Rao, Srinivasa P. S., Dick, Thomas, Alonso, Sylvie, Pethe, Kevin
Publicado em 2013

Correction: Characterization of Phosphofructokinase Activity in Mycobacterium tuberculosis Reveals That a Functional Glycolytic Carbon Flow Is Necessary to Limit the Accumulation o...

Por Phong, Wai Yee, Lin, Wenwei, Rao, Srinivasa P. S., Dick, Thomas, Alonso, Sylvie, Pethe, Kevin
Publicado em 2013

Targeting Lipid Esterases in Mycobacteria Grown Under Different Physiological Conditions Using Activity-based Profiling with Tetrahydrolipstatin (THL)

Por Ravindran, Madhu Sudhan, Rao, Srinivasa P. S., Cheng, Xiamin, Shukla, Ankit, Cazenave-Gassiot, Amaury, Yao, Shao Q., Wenk, Markus R.
Publicado em 2014

A novel F(420)-dependent anti-oxidant mechanism protects Mycobacterium tuberculosis against oxidative stress and bactericidal agents

Por Gurumurthy, Meera, Rao, Martin, Mukherjee, Tathagata, Rao, Srinivasa P S, Boshoff, Helena I, Dick, Thomas, Barry, Clifton E, Manjunatha, Ujjini H
Publicado em 2013

Lipid Droplet-associated Proteins Are Involved in the Biosynthesis and Hydrolysis of Triacylglycerol in Mycobacterium bovis Bacillus Calmette-Guérin

Por Low, Kai Leng, Shui, Guanghou, Natter, Klaus, Yeo, Wee Kiang, Kohlwein, Sepp D., Dick, Thomas, Rao, Srinivasa P. S., Wenk, Markus R.
Publicado em 2010

Variations of Subunit ε of the Mycobacterium tuberculosis F(1)F(o) ATP Synthase and a Novel Model for Mechanism of Action of the Tuberculosis Drug TMC207

Por Biuković, Goran, Basak, Sandip, Manimekalai, Malathy Sony Subramanian, Rishikesan, Sankaranarayanan, Roessle, Manfred, Dick, Thomas, Rao, Srinivasa P. S., Hunke, Cornelia, Grüber, Gerhard
Publicado em 2013

African trypanosomiasis: Synthesis & SAR enabling novel drug discovery of ubiquinol mimics for trypanosome alternative oxidase

Por West, Ryan A., O'Doherty, Oran G., Askwith, Trevor, Atack, John, Beswick, Paul, Laverick, Jamie, Paradowski, Michael, Pennicott, Lewis E., Rao, Srinivasa P.S., Williams, Gareth, Ward, Simon E.
Publicado no Eur J Med Chem (2017)

Exploring the Mode of Action of Bioactive Compounds by Microfluidic Transcriptional Profiling in Mycobacteria

Por Murima, Paul, de Sessions, Paola Florez, Lim, Vivian, Naim, Ahmad Nazri Mohamed, Bifani, Pablo, Boshoff, Helena I. M., Sambandamurthy, Vasan K., Dick, Thomas, Hibberd, Martin L., Schreiber, Mark, Rao, Srinivasa P. S.
Publicado em 2013

Direct inhibitors of InhA active against Mycobacterium tuberculosis

Por Manjunatha, Ujjini H., Rao, Srinivasa P. S., Kondreddi, Ravinder Reddy, Noble, Christian G., Camacho, Luis R., Tan, Bee H., Ng, Seow H., Ng, Pearly Shuyi, Ma, N. L., Lakshminarayana, Suresh B., Herve, Maxime, Barnes, S. Whitney, Yu, Weixuan, Kuhen, Kelli, Blasco, Francesca, Beer, David, Walker, John R., Tonge, Peter J., Glynne, Richard, Smith, Paul W., Diagana, Thierry T.
Publicado no Sci Transl Med (2015)

A High-Throughput Screen To Identify Inhibitors of ATP Homeostasis in Non-replicating Mycobacterium tuberculosis

Por Mak, Puiying A., Rao, Srinivasa P. S., Ping Tan, Mai, Lin, Xiuhua, Chyba, Jason, Tay, Joann, Ng, Seow Hwee, Tan, Bee Huat, Cherian, Joseph, Duraiswamy, Jeyaraj, Bifani, Pablo, Lim, Vivian, Lee, Boon Heng, Ling Ma, Ngai, Beer, David, Thayalan, Pamela, Kuhen, Kelli, Chatterjee, Arnab, Supek, Frantisek, Glynne, Richard, Zheng, Jun, Boshoff, Helena I., Barry, Clifton E., Dick, Thomas, Pethe, Kevin, Camacho, Luis R.
Publicado em 2012

Corrrection to Discovery of Tetrahydropyrazolopyrimidine Carboxamide Derivatives As Potent and Orally Active Novel Antitubercular Agents

Por Yokokawa, Fumiaki, Wang, Gang, Chan, Wai Ling, Ang, Shi Hua, Wong, Josephine, Ma, Ida, Rao, Srinivasa P S, Manjunatha, Ujjini, Lakshminarayana, Suresh B, Herve, Maxime, Kounde, Cyrille, Tan, Bee Huat, Thayalan, Pamela, Dick, Thomas, Ng, Seow Hwee, Nanjundappa, Mahesh, Ravindran, Sindhu, Gee, Peck, Tan, Maria, Wei, Liu, Goh, Anne, Chen, Pei-Yu, Lee, Kok Sin, Zhang, Chen, Wagner, Trixie, Dix, Ina, Chatterjee, Arnab, Pethe, Kevin, Kuhen, Kelli, Glynne, Richard, Smith, Paul, Bifani, Pablo, Jiricek, Jan
Publicado em 2014

Discovery of Tetrahydropyrazolopyrimidine Carboxamide Derivatives As Potent and Orally Active Antitubercular Agents

Por Yokokawa, Fumiaki, Wang, Gang, Chan, Wai Ling, Ang, Shi Hua, Wong, Josephine, Ma, Ida, Rao, Srinivasa P S, Manjunatha, Ujjini, Lakshminarayana, Suresh B, Herve, Maxime, Kounde, Cyrille, Tan, Bee Huat, Thayalan, Pamela, Ng, Seow Hwee, Nanjundappa, Mahesh, Ravindran, Sindhu, Gee, Peck, Tan, Maria, Wei, Liu, Goh, Anne, Chen, Pei-Yu, Lee, Kok Sin, Zhong, Chen, Wagner, Trixie, Dix, Ina, Chatterjee, Arnab K., Pethe, Kevin, Kuhen, Kelli, Glynne, Richard, Smith, Paul, Bifani, Pablo, Jiricek, Jan
Publicado em 2013

Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness

Por Khare, Shilpi, Nagle, Advait S., Biggart, Agnes, Lai, Yin H., Liang, Fang, Davis, Lauren C., Barnes, S. Whitney, Mathison, Casey J. N., Myburgh, Elmarie, Gao, Mu-Yun, Gillespie, J. Robert, Liu, Xianzhong, Tan, Jocelyn L., Stinson, Monique, Rivera, Ianne C., Ballard, Jaime, Yeh, Vince, Groessl, Todd, Federe, Glenn, Koh, Hazel X. Y., Venable, John D., Bursulaya, Badry, Shapiro, Michael, Mishra, Pranab K., Spraggon, Glen, Brock, Ansgar, Mottram, Jeremy C., Buckner, Frederick S., Rao, Srinivasa P. S., Wen, Ben G., Walker, John R., Tuntland, Tove, Molteni, Valentina, Glynne, Richard J., Supek, Frantisek
Publicado no Nature (2016)

A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy

Por Pethe, Kevin, Sequeira, Patricia C., Agarwalla, Sanjay, Rhee, Kyu, Kuhen, Kelli, Phong, Wai Yee, Patel, Viral, Beer, David, Walker, John R., Duraiswamy, Jeyaraj, Jiricek, Jan, Keller, Thomas H., Chatterjee, Arnab, Tan, Mai Ping, Ujjini, Manjunatha, Rao, Srinivasa P.S., Camacho, Luis, Bifani, Pablo, Mak, Puiying A., Ma, Ida, Barnes, S. Whitney, Chen, Zhong, Plouffe, David, Thayalan, Pamela, Ng, Seow Hwee, Au, Melvin, Lee, Boon Heng, Tan, Bee Huat, Ravindran, Sindhu, Nanjundappa, Mahesh, Lin, Xiuhua, Goh, Anne, Lakshminarayana, Suresh B., Shoen, Carolyn, Cynamon, Michael, Kreiswirth, Barry, Dartois, Veronique, Peters, Eric C., Glynne, Richard, Brenner, Sydney, Dick, Thomas
Publicado em 2010