African trypanosomiasis: Synthesis & SAR enabling novel drug discovery of ubiquinol mimics for trypanosome alternative oxidase

African trypanosomiasis is a parasitic disease affecting 5000 humans and millions of livestock animals in sub-Saharan Africa every year. Current treatments are limited, difficult to administer and often toxic causing long term injury or death in many patients. Trypanosome alternative oxidase is a pa...

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Detalhes bibliográficos
Publicado no:Eur J Med Chem
Main Authors: West, Ryan A., O'Doherty, Oran G., Askwith, Trevor, Atack, John, Beswick, Paul, Laverick, Jamie, Paradowski, Michael, Pennicott, Lewis E., Rao, Srinivasa P.S., Williams, Gareth, Ward, Simon E.
Formato: Artigo
Idioma:Inglês
Publicado em: Editions Scientifiques Elsevier 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697954/
https://ncbi.nlm.nih.gov/pubmed/29107420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2017.09.067
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