A novel F(420)-dependent anti-oxidant mechanism protects Mycobacterium tuberculosis against oxidative stress and bactericidal agents

Por Gurumurthy, Meera, Rao, Martin, Mukherjee, Tathagata, Rao, Srinivasa P S, Boshoff, Helena I, Dick, Thomas, Barry, Clifton E, Manjunatha, Ujjini H
Publicado em 2013

HEXIM1 Induces Differentiation of Human Pluripotent Stem Cells

Por Ding, Vanessa, Lew, Qiao Jing, Chu, Kai Ling, Natarajan, Subaashini, Rajasegaran, Vikneswari, Gurumurthy, Meera, Choo, Andre B. H., Chao, Sheng-Hao
Publicado em 2013

XBP-1, a Novel Human T-Lymphotropic Virus Type 1 (HTLV-1) Tax Binding Protein, Activates HTLV-1 Basal and Tax-Activated Transcription

Por Ku, Sebastian C. Y., Lee, Jialing, Lau, Joanne, Gurumurthy, Meera, Ng, Raymond, Lwa, Siew Hui, Lee, Joseph, Klase, Zachary, Kashanchi, Fatah, Chao, Sheng-Hao
Publicado em 2008

Identification of HEXIM1 as a Positive Regulator of p53

Por Lew, Qiao Jing, Chia, Yi Ling, Chu, Kai Ling, Lam, Yuen Ting, Gurumurthy, Meera, Xu, Shengli, Lam, Kong Peng, Cheong, Nge, Chao, Sheng-Hao
Publicado em 2012

Coadministration of Allopurinol To Increase Antimycobacterial Efficacy of Pyrazinamide as Evaluated in a Whole-Blood Bactericidal Activity Model

Por Naftalin, Claire M., Verma, Rupangi, Gurumurthy, Meera, Lu, Qingshu, Zimmerman, Matthew, Yeo, Benjamin Chaik Meng, Tan, Kin Hup, Lin, Wenwei, Yu, Buduo, Dartois, Véronique, Paton, Nicholas I.
Publicado no Antimicrob Agents Chemother (2017)

Substrate specificity of the Deazaflavin-Dependent Nitroreductase (Ddn) from Mycobacterium tuberculosis Responsible for the Bioreductive Activation of Bicyclic Nitroimidazoles

Por Gurumurthy, Meera, Mukherjee, Tathagata, Dowd, Cynthia S., Singh, Ramandeep, Niyomrattanakit, Pornwaratt, Tay, Jo Ann, Nayyar, Amit, Lee, Yong Sok, Cherian, Joseph, Boshoff, Helena I., Dick, Thomas, Barry, Clifton E., Manjunatha, Ujjini H.
Publicado em 2011

Pharmacokinetics-Pharmacodynamics Analysis of Bicyclic 4-Nitroimidazole Analogs in a Murine Model of Tuberculosis

Por Lakshminarayana, Suresh B., Boshoff, Helena I. M., Cherian, Joseph, Ravindran, Sindhu, Goh, Anne, Jiricek, Jan, Nanjundappa, Mahesh, Nayyar, Amit, Gurumurthy, Meera, Singh, Ramandeep, Dick, Thomas, Blasco, Francesca, Barry, Clifton E., Ho, Paul C., Manjunatha, Ujjini H.
Publicado em 2014

Structure of Ddn, the Deazaflavin-Dependent Nitroreductase from Mycobacterium tuberculosis Involved in Bioreductive Activation of PA-824

Por Cellitti, Susan E., Shaffer, Jennifer, Jones, David H., Mukherjee, Tathagata, Gurumurthy, Meera, Bursulaya, Badry, Boshoff, Helena I., Choi, Inhee, Nayyar, Amit, Lee, Yong Sok, Cherian, Joseph, Niyomrattanakit, Pornwaratt, Dick, Thomas, Manjunatha, Ujjini H., Barry, Clifton E., Spraggon, Glen, Geierstanger, Bernhard H.
Publicado em 2012

Structure of Ddn, the Deazaflavin-Dependent Nitroreductase from Mycobacterium tuberculosis Involved in Bioreductive Activation of PA-824

Por Cellitti, Susan E., Shaffer, Jennifer, Jones, David H., Mukherjee, Tathagata, Gurumurthy, Meera, Bursulaya, Badry, Boshoff, Helena I., Choi, Inhee, Nayyar, Amit, Lee, Yong Sok, Cherian, Joseph, Niyomrattanakit, Pornwaratt, Dick, Thomas, Manjunatha, Ujjini H., Barry, Clifton E., Spraggon, Glen, Geierstanger, Bernhard H.
Publicado no Structure (2013)