Caught between two proteins: a mycobacterial inhibitor challenges the mold

Por Boshoff, Helena I.
Publicado no Mol Microbiol (2016)

Mechanisms underlying mycobacterial infections

Por Boshoff, Helena I., Tahlan, Kapil
Publicado em 2010

Systems biological approaches in infectious diseases

Por Boshoff, Helena I., Barry, Clifton E.
Publicado em 2007

Purification, Gene Cloning, Targeted Knockout, Overexpression, and Biochemical Characterization of the Major Pyrazinamidase from Mycobacterium smegmatis

Por Boshoff, Helena I. M., Mizrahi, Valerie
Publicado em 1998

Expression of Mycobacterium smegmatis Pyrazinamidase in Mycobacterium tuberculosis Confers Hypersensitivity to Pyrazinamide and Related Amides

Por Boshoff, Helena I. M., Mizrahi, Valerie
Publicado em 2000

Systems biology approaches to understanding mycobacterial survival mechanisms

Por Boshoff, Helena I.M., Lun, Desmond S.
Publicado em 2010

Effects of Pyrazinamide on Fatty Acid Synthesis by Whole Mycobacterial Cells and Purified Fatty Acid Synthase I

Por Boshoff, Helena I., Mizrahi, Valerie, Barry, Clifton E.
Publicado em 2002

The Three RelE Homologs of Mycobacterium tuberculosis Have Individual, Drug-Specific Effects on Bacterial Antibiotic Tolerance

Por Singh, Ramandeep, Barry, Clifton E., Boshoff, Helena I. M.
Publicado em 2010

Para-Aminosalicylic Acid Acts as an Alternative Substrate of Folate Metabolism in Mycobacterium tuberculosis

Por Chakraborty, Sumit, Gruber, Todd, Barry, Clifton E., Boshoff, Helena I., Rhee, Kyu Y.
Publicado em 2012

Investigation and Conformational Analysis of Fluorinated Nucleoside Antibiotics Targeting Siderophore Biosynthesis

Por Dawadi, Surendra, Viswanathan, Kishore, Boshoff, Helena I., Barry, Clifton E., Aldrich, Courtney C.
Publicado no J Org Chem (2015)

Meropenem-Clavulanate Is Effective Against Extensively Drug-Resistant Mycobacterium tuberculosis

Por Hugonnet, Jean-Emmanuel, Tremblay, Lee W., Boshoff, Helena I., Barry, Clifton E., Blanchard, John S.
Publicado em 2009

HIV-1 Replication Is Differentially Regulated by Distinct Clinical Strains of Mycobacterium tuberculosis

Por Ranjbar, Shahin, Boshoff, Helena I., Mulder, Amara, Siddiqi, Noman, Rubin, Eric J., Goldfeld, Anne E.
Publicado em 2009

Fumarate Reductase Activity Maintains an Energized Membrane in Anaerobic Mycobacterium tuberculosis

Por Watanabe, Shinya, Zimmermann, Michael, Goodwin, Michael B., Sauer, Uwe, Barry, Clifton E., Boshoff, Helena I.
Publicado em 2011

The Mycobacterium tuberculosis β-oxidation genes echA5 and fadB3 are dispensable for growth in vitro and in vivo

Por Williams, Kerstin J., Boshoff, Helena I., Krishnan, Nitya, Gonzales, Jacqueline, Schnappinger, Dirk, Robertson, Brian D.
Publicado em 2011

Synthesis and antimalarial and antituberculosis activities of a series of natural and unnatural 4-methoxy-6-styryl-pyran-2-ones, dihydro analogues and photodimers

Por McCracken, Stephen T., Kaiser, Marcel, Boshoff, Helena I., Boyd, Peter D. W., Copp, Brent R.
Publicado em 2012

Design, Synthesis and Biological Evaluation of β-Ketosulfonamide Adenylation Inhibitors as Potential Antitubercular Agents

Por Vannada, Jagadeshwar, Bennett, Eric M., Wilson, Daniel, Boshoff, Helena I., Barry, Clifton E., Aldrich, Courtney C.
Publicado em 2006

Proteasomal Protein Degradation in Mycobacteria Is Dependent upon a Prokaryotic Ubiquitin-like Protein

Por Burns, Kristin E., Liu, Wei-Ting, Boshoff, Helena I. M., Dorrestein, Pieter C., Barry, Clifton E.
Publicado em 2009

Structure-activity relationships of 2-aminothiazoles effective against Mycobacterium tuberculosis

Por Meissner, Anja, Boshoff, Helena I., Vasan, Mahalakshmi, Duckworth, Benjamin P., Barry, Clifton E., Aldrich, Courtney C.
Publicado em 2013

Bioluminescent Reporters for Rapid Mechanism of Action Assessment in Tuberculosis Drug Discovery

Por Naran, Krupa, Moosa, Atica, Barry, Clifton E., Boshoff, Helena I. M., Mizrahi, Valerie, Warner, Digby F.
Publicado no Antimicrob Agents Chemother (2016)

Preparation and Evaluation of Potent Pentafluorosulfanyl Substituted Anti-Tuberculosis Compounds

Por Moraski, Garrett C., Bristol, Ryan, Seeger, Natalie, Boshoff, Helena I., Tsang, Patricia Siu-Yee, Miller, Marvin J.
Publicado no ChemMedChem (2017)