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Fumarate Reductase Activity Maintains an Energized Membrane in Anaerobic Mycobacterium tuberculosis

Oxygen depletion of Mycobacterium tuberculosis engages the DosR regulon that coordinates an overall down-regulation of metabolism while up-regulating specific genes involved in respiration and central metabolism. We have developed a chemostat model of M. tuberculosis where growth rate was a function...

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Detalhes bibliográficos
Main Authors: Watanabe, Shinya, Zimmermann, Michael, Goodwin, Michael B., Sauer, Uwe, Barry, Clifton E., Boshoff, Helena I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188519/
https://ncbi.nlm.nih.gov/pubmed/21998585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002287
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