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Bioluminescent Reporters for Rapid Mechanism of Action Assessment in Tuberculosis Drug Discovery
The tuberculosis (TB) drug discovery pipeline is fueled by compounds identified in whole-cell screens against the causative agent, Mycobacterium tuberculosis. Phenotypic screening enables the selection of molecules that inhibit essential cellular functions in live, intact bacilli grown under a chose...
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| Udgivet i: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5075082/ https://ncbi.nlm.nih.gov/pubmed/27572410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01178-16 |
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