Mycobacterium tuberculosis Metabolism

gan Warner, Digby F.
Cyhoeddwyd yn Cold Spring Harb Perspect Med (2015)

Tuberculosis Chemotherapy: the Influence of Bacillary Stress and Damage Response Pathways on Drug Efficacy

gan Warner, Digby F., Mizrahi, Valerie
Cyhoeddwyd 2006

Translating genomics research into control of tuberculosis: lessons learned and future prospects

gan Warner, Digby F, Mizrahi, Valerie
Cyhoeddwyd yn Genome Biol (2014)

Death of Mycobacterium tuberculosis by l-arginine starvation

gan Mizrahi, Valerie, Warner, Digby F.
Cyhoeddwyd yn Proc Natl Acad Sci U S A (2018)

The impact of drug resistance on Mycobacterium tuberculosis physiology: what can we learn from rifampicin?

gan Koch, Anastasia, Mizrahi, Valerie, Warner, Digby F
Cyhoeddwyd 2014

DNA Replication in Mycobacterium tuberculosis

gan DITSE, ZANELE, LAMERS, MEINDERT H., WARNER, DIGBY F.
Cyhoeddwyd yn Microbiol Spectr (2017)

Targeting DNA Replication and Repair for the Development of Novel Therapeutics against Tuberculosis

gan Reiche, Michael A., Warner, Digby F., Mizrahi, Valerie
Cyhoeddwyd yn Front Mol Biosci (2017)

A Riboswitch Regulates Expression of the Coenzyme B(12)-Independent Methionine Synthase in Mycobacterium tuberculosis: Implications for Differential Methionine Synthase Function in...

gan Warner, Digby F., Savvi, Suzana, Mizrahi, Valerie, Dawes, Stephanie S.
Cyhoeddwyd 2007

Drug permeation and metabolism in Mycobacterium tuberculosis: prioritising local exposure as essential criterion in new TB drug development

gan Tanner, Lloyd, Denti, Paolo, Wiesner, Lubbe, Warner, Digby F.
Cyhoeddwyd yn IUBMB Life (2018)

Harnessing Biological Insight to Accelerate Tuberculosis Drug Discovery

gan de Wet, Timothy J., Warner, Digby F., Mizrahi, Valerie
Cyhoeddwyd yn Acc Chem Res (2019)

Addressing Latent Tuberculosis: New Advances in Mimicking the Disease, Discovering Key Targets, and Designing Hit Compounds

gan Campaniço, André, Harjivan, Shrika G., Warner, Digby F., Moreira, Rui, Lopes, Francisca
Cyhoeddwyd yn Int J Mol Sci (2020)

Function and Regulation of Class I Ribonucleotide Reductase-Encoding Genes in Mycobacteria

gan Mowa, Mohube B., Warner, Digby F., Kaplan, Gilla, Kana, Bavesh D., Mizrahi, Valerie
Cyhoeddwyd 2009

Arrayed CRISPRi and quantitative imaging describe the morphotypic landscape of essential mycobacterial genes

gan de Wet, Timothy J, Winkler, Kristy R, Mhlanga, Musa, Mizrahi, Valerie, Warner, Digby F
Cyhoeddwyd yn eLife (2020)

Functional Characterization of a Vitamin B(12)-Dependent Methylmalonyl Pathway in Mycobacterium tuberculosis: Implications for Propionate Metabolism during Growth on Fatty Acids

gan Savvi, Suzana, Warner, Digby F., Kana, Bavesh D., McKinney, John D., Mizrahi, Valerie, Dawes, Stephanie S.
Cyhoeddwyd 2008

Bioluminescent Reporters for Rapid Mechanism of Action Assessment in Tuberculosis Drug Discovery

gan Naran, Krupa, Moosa, Atica, Barry, Clifton E., Boshoff, Helena I. M., Mizrahi, Valerie, Warner, Digby F.
Cyhoeddwyd yn Antimicrob Agents Chemother (2016)

De Novo Cobalamin Biosynthesis, Transport, and Assimilation and Cobalamin-Mediated Regulation of Methionine Biosynthesis in Mycobacterium smegmatis

gan Kipkorir, Terry, Mashabela, Gabriel T., de Wet, Timothy J., Koch, Anastasia, Wiesner, Lubbe, Mizrahi, Valerie, Warner, Digby F.
Cyhoeddwyd yn J Bacteriol (2021)

New Quinolone-Based Thiosemicarbazones Showing Activity Against Plasmodium falciparum and Mycobacterium tuberculosis

gan Beteck, Richard M., Seldon, Ronnett, Jordaan, Audrey, Warner, Digby F., Hoppe, Heinrich C., Laming, Dustin, Khanye, Setshaba D.
Cyhoeddwyd yn Molecules (2019)

Easy-To-Access Quinolone Derivatives Exhibiting Antibacterial and Anti-Parasitic Activities

gan Beteck, Richard M., Jordaan, Audrey, Seldon, Ronnett, Laming, Dustin, Hoppe, Heinrich C., Warner, Digby F., Khanye, Setshaba D.
Cyhoeddwyd yn Molecules (2021)

Ribonucleotide Reduction in Mycobacterium tuberculosis: Function and Expression of Genes Encoding Class Ib and Class II Ribonucleotide Reductases

gan Dawes, Stephanie S., Warner, Digby F., Tsenova, Liana, Timm, Juliano, McKinney, John D., Kaplan, Gilla, Rubin, Harvey, Mizrahi, Valerie
Cyhoeddwyd 2003

Essential roles for imuA′- and imuB-encoded accessory factors in DnaE2-dependent mutagenesis in Mycobacterium tuberculosis

gan Warner, Digby F., Ndwandwe, Duduzile E., Abrahams, Garth L., Kana, Bavesh D., Machowski, Edith E., Venclovas, Česlovas, Mizrahi, Valerie
Cyhoeddwyd 2010