Function and Regulation of Class I Ribonucleotide Reductase-Encoding Genes in Mycobacteria

Ribonucleotide reductases (RNRs) are crucial to all living cells, since they provide deoxyribonucleotides (dNTPs) for DNA synthesis and repair. In Mycobacterium tuberculosis, a class Ib RNR comprising nrdE- and nrdF2-encoded subunits is essential for growth in vitro. Interestingly, the genome of thi...

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Detalhes bibliográficos
Main Authors: Mowa, Mohube B., Warner, Digby F., Kaplan, Gilla, Kana, Bavesh D., Mizrahi, Valerie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Molecular Biology of Pathogens
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632068/
https://ncbi.nlm.nih.gov/pubmed/19028890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01409-08
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