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Function and Regulation of Class I Ribonucleotide Reductase-Encoding Genes in Mycobacteria
Ribonucleotide reductases (RNRs) are crucial to all living cells, since they provide deoxyribonucleotides (dNTPs) for DNA synthesis and repair. In Mycobacterium tuberculosis, a class Ib RNR comprising nrdE- and nrdF2-encoded subunits is essential for growth in vitro. Interestingly, the genome of thi...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2632068/ https://ncbi.nlm.nih.gov/pubmed/19028890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01409-08 |
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