Essential roles for imuA′- and imuB-encoded accessory factors in DnaE2-dependent mutagenesis in Mycobacterium tuberculosis

In Mycobacterium tuberculosis (Mtb), damage-induced mutagenesis is dependent on the C-family DNA polymerase, DnaE2. Included with dnaE2 in the Mtb SOS regulon is a putative operon comprising Rv3395c, which encodes a protein of unknown function restricted primarily to actinomycetes, and Rv3394c, whic...

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Bibliographic Details
Main Authors: Warner, Digby F., Ndwandwe, Duduzile E., Abrahams, Garth L., Kana, Bavesh D., Machowski, Edith E., Venclovas, Česlovas, Mizrahi, Valerie
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919956/
https://ncbi.nlm.nih.gov/pubmed/20615954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002614107
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