Functional Characterization of a Vitamin B(12)-Dependent Methylmalonyl Pathway in Mycobacterium tuberculosis: Implications for Propionate Metabolism during Growth on Fatty Acids

Mycobacterium tuberculosis is predicted to subsist on alternative carbon sources during persistence within the human host. Catabolism of odd- and branched-chain fatty acids, branched-chain amino acids, and cholesterol generates propionyl-coenzyme A (CoA) as a terminal, three-carbon (C(3)) product. P...

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Dades bibliogràfiques
Autors principals: Savvi, Suzana, Warner, Digby F., Kana, Bavesh D., McKinney, John D., Mizrahi, Valerie, Dawes, Stephanie S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
Matèries:
Physiology and Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2395058/
https://ncbi.nlm.nih.gov/pubmed/18375549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01767-07
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