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Investigation and Conformational Analysis of Fluorinated Nucleoside Antibiotics Targeting Siderophore Biosynthesis

Antibiotic resistance represents one of the greatest threats to public health. The adenylation inhibitor 5′-O-[N-(salicyl)sulfamoyl]adenosine (SAL-AMS) is the archetype for a new class of nucleoside antibiotics that target iron acquisition in pathogenic microorganisms and is especially effective aga...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Dawadi, Surendra, Viswanathan, Kishore, Boshoff, Helena I., Barry, Clifton E., Aldrich, Courtney C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674167/
https://ncbi.nlm.nih.gov/pubmed/25916415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.5b00550
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