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Antitubercular Nucleosides that Inhibit Siderophore Biosynthesis: SAR of the Glycosyl Domain

Tuberculosis (TB) is the leading cause of infectious disease mortality in the world by a bacterial pathogen. We previously demonstrated that a bisubstrate inhibitor of the adenylation enzyme MbtA, which is responsible for the second step of mycobactin biosynthesis, exhibited potent antitubercular ac...

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Detalhes bibliográficos
Main Authors: Somu, Ravindranadh V., Wilson, Daniel, Bennett, Eric M., Boshoff, Helena, Celia, Laura, Beck, Brian, Barry, Clifton E., Aldrich, Courtney C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526467/
https://ncbi.nlm.nih.gov/pubmed/17181146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm061068d
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