Antitubercular Nucleosides that Inhibit Siderophore Biosynthesis: SAR of the Glycosyl Domain

Tuberculosis (TB) is the leading cause of infectious disease mortality in the world by a bacterial pathogen. We previously demonstrated that a bisubstrate inhibitor of the adenylation enzyme MbtA, which is responsible for the second step of mycobactin biosynthesis, exhibited potent antitubercular ac...

Full description

Saved in:
Bibliographic Details
Main Authors: Somu, Ravindranadh V., Wilson, Daniel, Bennett, Eric M., Boshoff, Helena, Celia, Laura, Beck, Brian, Barry, Clifton E., Aldrich, Courtney C.
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526467/
https://ncbi.nlm.nih.gov/pubmed/17181146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm061068d
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items